Yearly Archives: 2024

3D Bone and Cartilage Models to Understand Tissue Regeneration

This month, we sat down with Dr. Johanna Bolander. Dr. Bolander has a PhD in Regenerative Medicine from K.U Leuven and a postdoc at the MERLN Institute of Technology in Maastricht, as well as the Wake Forest Institute for Regenerative Medicine in North Carolina. Currently, she is an Assistant Professor at Charité Hospital in Berlin, as well as a Principal Member of the Technical Staff at imec. Dr. Bolander is an expert in bone and cartilage tissue and uses 3D models to investigate why certain tissues fail to heal. Her joint positions give her the unique opportunity todevelop solutions from both a biological and technical perspective.

Ultra-Miniaturized Primary Hepatocyte Spheroids for Early-Stage Drug Discovery 

This month, we sat down with Dr. Brinton Seashore-Ludlow. Dr. Seashore-Ludlow has a PhD in organic chemistry and synthetic methods from The Royal Institute of Technology (KTH) in Stockholm and did a postdoc at the Broad Institute of Harvard and MIT. Currently, she is a Senior Researcher at Karolinska Institutet and the Chemical Biology Consortium of Sweden focusing on precision cancer medicine.

3D Models of the Most Communicative Organ in the Body: Fat

This month, we sat down with Dr. Elvira Weber, adipose tissue organoid pioneer, expert in regenerative medicine, and Head of Lab at the CURE 3D lab in Düsseldorf.  

The Key to Moving 3D Culture Forward

This month, we sat down with Dr. Maryna Panamarova, a technical expert in the 3D culture space. Dr. Panamarova is working to develop and upscale novel organoid models at the Wellcome Sanger Institute. She is an advocate for making knowledge open source and believes it’s key to advancing the industry forward. 

A vision for animal-free drug testing with Dr. Tamara Zietek

This month, we sat down with Dr. Tamara Zietek, a pioneer in 3D intestinal modelling and a leading voice pushing for the replacement of animal testing in life science with New Approach Methodologies (NAMs). We discuss her journey, the evolution of in-vitro 3D models, regulatory hurdles, and how we can achieve a paradigm shift in drug development. 

The need for standardization in 3D cell culture (let’s start small)

In the realm of 3D cell culture, the diversity of terminology – from organoids and tumoroids to spheroids and Microphysiological Systems (MPS) – reflects innovation but also creates barriers to communication and adoption.